Table 3 Recurrent mutations in BRCA1/2 detected in 398 probands with epithelial ovarian cancer
Mutation/times detected | Unrelated probands (% of the total probands) |
|---|---|
BRCA1 | |
c.4964_4982del19 - p.(Ser1655Tyrfs*16)/5 | 5 (1.3) |
c.5266dupC - p.(Gln1756Profs*74)/3 | 3 (0.8) |
BRCA2 | |
c.5351dupA - p.(Asn1784Lysfs*3)/4 | 4 (1.0) |
Total recurrent | 12 (3.1) |
Total recurrent (12)/total mutated (96) = 12.5% | – |