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Table 1 Clinical and biochemical characterization of the study subjects

From: Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes

Parameter Normal glucose tolerance [NGT] (n = 32) Type 2 diabetes mellitus [T2DM] (n = 30) p value
Age (years) 44 ± 8 46 ± 8 0.218
Gender—male (female) 18 (14) 18 (12)
Body mass index (kg/m2) 25 ± 3.1 27 ± 4 0.015
Waist circumference (cm) 85 ± 8 94 ± 9 < 0.001
Fasting plasma glucose (mg/dL) 87 ± 9 136 ± 24 < 0.001
Glycated hemoglobin—HbA1c (%) 5.6 ± 0.34 8.1 ± 1.9 < 0.001
HOMA-IR 1.8 ± 0.8 6.9 ± 3 < 0.001
Fasting insulin (μIU/mL) 8.6 ± 3.5 22 ± 7.2 < 0.001
Systolic blood pressure (mmHg) 120 ± 25 131 ± 21 0.079
Diastolic blood pressure (mmHg) 79 ± 13 80 ± 8 0.795
Total cholesterol (mg/dL) 174 ± 28 169 ± 37 0.545
Serum triglycerides (mg/dL) 132 ± 71 138 ± 49 0.737
HDL cholesterol (mg/dL) 41 ± 10 39 ± 7 0.352
LDL cholesterol (mg/dL) 107 ± 21 102 ± 34 0.568
VLDL 27 ± 14 28 ± 10 0.732
  1. Data represented as mean ± SD. Italicized value represents statistically significant compared to NGT