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Table 1 Clinical and biochemical characterization of the study subjects

From: Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes

Parameter

Normal glucose tolerance [NGT] (n = 32)

Type 2 diabetes mellitus [T2DM] (n = 30)

p value

Age (years)

44 ± 8

46 ± 8

0.218

Gender—male (female)

18 (14)

18 (12)

–

Body mass index (kg/m2)

25 ± 3.1

27 ± 4

0.015

Waist circumference (cm)

85 ± 8

94 ± 9

< 0.001

Fasting plasma glucose (mg/dL)

87 ± 9

136 ± 24

< 0.001

Glycated hemoglobin—HbA1c (%)

5.6 ± 0.34

8.1 ± 1.9

< 0.001

HOMA-IR

1.8 ± 0.8

6.9 ± 3

< 0.001

Fasting insulin (μIU/mL)

8.6 ± 3.5

22 ± 7.2

< 0.001

Systolic blood pressure (mmHg)

120 ± 25

131 ± 21

0.079

Diastolic blood pressure (mmHg)

79 ± 13

80 ± 8

0.795

Total cholesterol (mg/dL)

174 ± 28

169 ± 37

0.545

Serum triglycerides (mg/dL)

132 ± 71

138 ± 49

0.737

HDL cholesterol (mg/dL)

41 ± 10

39 ± 7

0.352

LDL cholesterol (mg/dL)

107 ± 21

102 ± 34

0.568

VLDL

27 ± 14

28 ± 10

0.732

  1. Data represented as mean ± SD. Italicized value represents statistically significant compared to NGT