Fig. 4
From: Impact of ZBTB7A hypomethylation and expression patterns on treatment response to hydroxyurea
Mean methylation rate of CpG sites in single BFU-E colonies before and after HU treatment among all in vitro groups of samples (Table 2). a ZBTB7A CpG 326 and GATA2 CpG 515 showed a significant hypomethylation profile in non-responders (NRs). b SIN3A CpG 401, KLF1 CpG 98, and BCL11A CpG 115 showed hypomethylation trend in NRs, though not of statistical significance. Data are presented as boxplots. Boxes represent the 25th and the 75th percentiles of total values. They include the maximum and minimum values, the median value of the data set (lines inside the boxes), the most extreme values (*), the outliers (°), and the significant p* values recorded. BM, CG, NR, R, and UCB indicate BFU-Es derived from bone marrow, control group, HU non-responders, HU responders, and umbilical cord blood respectively