Fig. 5
From: Impact of ZBTB7A hypomethylation and expression patterns on treatment response to hydroxyurea
Relative expression of LRF/ZBTB7A and statistical correlations between gene’s methylation and expression. a Relative expression of LRF/ZBTB7A in BFU-E colonies of responders and non-responders (III R1–5, III NR1–4) after HU treatment. b Correlation between methylation and gene expression results in responders and non-responders (III R1–5, III NR1–4). Hypomethylation results in ZBTB7A CpG 326 were in line with the higher expression of ZBTB7A observed in non-responders. Opposite results were detected in the responders’ group