Table 2 In vitro samples (III and IV)
From: Impact of ZBTB7A hypomethylation and expression patterns on treatment response to hydroxyurea
Sample ID | In vitro γ-globin (+HU/−HU) | Baseline HbF (−HU) | Plateau HbF (+HU) | In vivo HbF (+HU)/(−HU) |
|---|---|---|---|---|
IV CG1 | 1.75 | x | x | x |
IV CG2 | 1.38 | x | x | x |
IV CG3 | 1.26 | x | x | x |
IV CG4 | 1.69 | x | x | x |
III NR1 | 1.35 | 3.4 | 4.6 | 1.35 |
III NR2 | 1.54 | 2.5 | 2.9 | 1.16 |
III NR3 | 2.12 | 0.6 | 1 | 1.67 |
III NR4 | 1.43 | 2.1 | 2.9 | 1.38 |
III R1 | 1.09 | 6.1 | 22.6 | 3.7 |
III R2 | 3.66 | 6.7 | 16.4 | 2.5 |
III R3 | 2.31 | 10.7 | 31 | 2.89 |
III R4 | 2.56 | 9.8 | 24.5 | 2.5 |
III R5 | 1.87 | 2.7 | 15.1 | 5.6 |
IV UCB1 | 2.02 | x | x | x |
IV UCB2 | 2.57 | x | x | x |
IV UCB3 | 1.96 | x | x | x |
IV UCB4 | 2.34 | x | x | x |
IV BM1 | 5.58 | x | x | x |
IV BM2 | 4.44 | x | x | x |
IV BM3 | 3.25 | x | x | x |
IV BM4 | 5.02 | x | x | x |