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Table 2 In vitro samples (III and IV)

From: Impact of ZBTB7A hypomethylation and expression patterns on treatment response to hydroxyurea

Sample ID In vitro γ-globin (+HU/−HU) Baseline HbF (−HU) Plateau HbF (+HU) In vivo HbF (+HU)/(−HU)
IV CG1 1.75 x x x
IV CG2 1.38 x x x
IV CG3 1.26 x x x
IV CG4 1.69 x x x
III NR1 1.35 3.4 4.6 1.35
III NR2 1.54 2.5 2.9 1.16
III NR3 2.12 0.6 1 1.67
III NR4 1.43 2.1 2.9 1.38
III R1 1.09 6.1 22.6 3.7
III R2 3.66 6.7 16.4 2.5
III R3 2.31 10.7 31 2.89
III R4 2.56 9.8 24.5 2.5
III R5 1.87 2.7 15.1 5.6
IV UCB1 2.02 x x x
IV UCB2 2.57 x x x
IV UCB3 1.96 x x x
IV UCB4 2.34 x x x
IV BM1 5.58 x x x
IV BM2 4.44 x x x
IV BM3 3.25 x x x
IV BM4 5.02 x x x