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Fig. 4 | Human Genomics

Fig. 4

From: Identification of drug repurposing candidates based on a miRNA-mediated drug and pathway network for cardiac hypertrophy and acute myocardial infarction

Fig. 4

Functional analyses and construction of a miRNA-mediated subnetwork. a The KEGG pathway enrichment results for all genes in the dysregulated MGDTs in the cardiac hypertrophy network ranked by − log10(P) are presented as bar plots. b The KEGG pathway enrichment results for all genes in the dysregulated MGDTs in the AMI network ranked by − log10(P) are presented as bar plots. c A bar plot showing the degrees of drugs in the cardiac hypertrophy network. d The IGFR1-centered subnetwork of the cardiac hypertrophy network. e A bar plot showing the degrees of drugs in the AMI network. f The VEGFA-centered subnetwork in the AMI network. g The heat maps show miRNA expression in the two subnetworks

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Human Genomics

ISSN: 1479-7364