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Table 2 TLR8 association studies from different populations

From: The X chromosome and sex-specific effects in infectious disease susceptibility

Study Cohort Case Control SNP Allele Gender OR* 95% CI* P value
Davila et al. [98] Indonesia 77 49 rs3764879 C Male 1.9 1.2–2.7 0.012
76 74 rs3764879 C Female 1.1 0.8–1.7 0.44
76 51 rs3761624 A Male 1.8 1.2–2.8 0.007
76 74 rs3761624 A Female 1.1 0.8–1.7 0.44
76 50 rs3788935 A Male 1.8 1.2–2.7 0.017
76 74 rs3788935 A Female 1.1 0.8–1.7 0.44
76 51 rs3764880 A Male 1.8 1.2–2.9 0.007
76 74 rs3764880 A Female 1.1 0.8–1.7 0.44
Russia 1067 994 rs3764879 C Male 1.2 1.02–1.48 0.03
1069 997 rs3788935 A Male 1.2 1.02–1.48 0.03
1070 1000 rs3761624 A Male 1.2 1.01–1.46 0.04
1069 997 rs3764880 A Male 1.2 1.02–1.48 0.03
Dalgic et al. [99] Turkish children 72 62 rs3764880 A Male 0.43 0.16–0.72 0.007
156 124 rs3764880 A Female NS NS NS
72 62 rs3764879 C Male NS NS NS
156 124 rs3764879 C Female NS NS NS
Hashemi-Shahri et al. [100] Iran 77 62 rs3764880 G Male 1.15 0.84–1.59 0.80
196 166 rs3764880 G Female 1.15 0.75–1.75 0.51
Bukhari et al. [101] Pakistan 45 22 rs3764880 A Male / / < 0.0001
58 65 rs3764880 A Female 0.363 0.199–0.660 0.0013
Salie et al. [97] SAC 204 99 rs3761624 A Male / / 0.164
217 336 rs3761624 A Female 1.54 1.19–1.99 < 0.001
205 99 rs3764879 C Male 0.72 0.55–0.93 0.013
220 334 rs3764879 C Female 1.41 1.08–1.83 0.011
1887 81 rs3764880 A Male 0.75 0.57–0.98 0.036
199 306 rs3764880 A Female 1.42 1.09–1.87 0.011
Lai et al. [102] Chinese 96 146 rs3764879 C Male 4.04 1.82–8.99 < 0.001
40 97 rs3764879 C Female 5.05 0.44–57.38 0.191
  1. OR odds ratio; 95% CI 95% confidence interval