The association of functional polymorphisms in genes expressed in endothelial cells and smooth muscle cells with the myocardial infarction

Table 1 Baseline characteristics of the individuals included in the study

Variables	MI (n = 401)	Controls (n = 409)	OR (95% CI)^a	p value^b
Age, years	58.20 (11.65)	56.34 (9.52)	0.84 (0.75-1.24)	0.223
Male sex, No. (%)	329 (82.0%)	339 (82.9%)	0.94 (0.66- 1.36)	0.753
Smoking, No. (%)	242 (60.3%)	187 (45.7%)	0.56 (0.37-0.72)	3.04E-05^c
Alcohol, No. (%)	105 (26.2%)	82 (20.0%)	0.62 (0.39-0.82)	0.038
Diabetes, No. (%)	99 (26.7%)	50 (12.2%)	0.43 (0.29-0.62)	4.71E-06
Hypertension, No. (%)	192 (47.9%)	143 (35.0%)	0.59 (0.44-0.78)	1.90E-4
Hypercholesterolemia, No. (%)	55 (13.7%)	39 (9.5%)	0.66 (0.43-1.03)	0.063
WBC, 10⁹/L	11.96 (3.81)	6.84 (1.90)	1.93 (1.76-2.12)	1.78E-80
FBG, mmol/L	6.44 (5.10, 8.88)	5.34 (4.93, 6.04)	1.15 (1.09-1.21)	1.25E-7
CRE, μmol/L	81.00 (69.00, 95.30)	71.00 (62.00, 80.00)	1.04 (1.03-1.05)	3.22E-18
AST, U/L	37.00 (22.00, 117.50)	24.00 (20.00, 28.00)	1.04 (1.03-1.05)	2.54E-32
Total cholesterol, mmol/L	4.56 (1.05)	4.96 (0.84)	0.65 (0.56-0.76)	7.03E-9
Triglycerides, mmol/L	1.38 (0.95,1.93)	1.32 (0.92, 2.02)	0.99 (0.88-1.11)	0.764
HDL cholesterol, mmol/L	1.23 (1.06, 1.43)	1.31 (1.13, 1.52)	0.50 (0.33-0.75)	1.65E-3
LDL cholesterol, mmol/L	2.77 (0.83)	3.30 (0.73)	0.44 (0.36-0.53)	1.92E-20

Values are mean ± SD or n (%), continuous variables that have skewed distribution are expressed as median (25, 75 percentiles)
Type 2 diabetes was diagnosed: (1) fasting plasma glucose (FPG) ≥ 7.0 mmol/L; (2) 2 h postprandial glucose ≥ 11.1 mmol/L; or (3) use of anti-diabetic medications. Hypertension was defined as systolic/diastolic blood pressure ≥ 140 mmHg or ≥ 90 mmHg or use of antihypertensive medications. Hypercholesterolemia was defined as use of cholesterol-lowering medications or total serum cholesterol > 200 mg/dl. WBC white blood cell, FBG fasting blood glucose, AST aspartate transaminase, CRE creatinine, HDL high-density lipoprotein, LDL low-density lipoprotein
^aBinary regression
^bTwo-sided chi-square test or independent-samples 푡 test
^cp values under 0.05 were shown in italic font

ISSN: 1479-7364