From: A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts
ALSPAC 6–9-year-olds (N = 3647) |  | |||||||||
rsID | Cluster | chr:pos_nonEA_EA | β (SE) P | β (SE) P (proxy) | Location | Nearby genes | Lead SNP locus (or distance to genes within 200 kb, in bp) | β (SE) P (CC)a | β (SE) P (MA1) | β (SE) P (MA2) |
rs139045492 | 20:22836201-22836202 | 20:22836202_G_A | − 0.695 (0.119) p = 6.35E−09 | – | Intergenic | . | SSTR4 (dist = 179,855) | − 0.489 (0.240) p = 0.042 | 0.080 (0.078) p = 0.306 | − 0.005 (0.097) p = 0.956 |
rs144874692 | 3:175689046-175689047 | 3:175689047_G_A | − 0.632 (0.112) p = 1.78E−08 | − 0.328 (0.105) p = 0.002 | Intergenic | . | NAALADL2 (dist = 165,619) | − 0.024 (0.263) p = 0.926 | Proxy: 0.00 (0.075) p = 1.00 | Proxy: 0.016 (0.094) p = 0.861 |
ALSPAC neonates (N = 2102) | ||||||||||
rsID | Cluster | chr:pos_nonEA_EA | β (SE) P | β (SE) P (Proxy) | Location | Nearby genes | Lead SNP locus (or distance to genes within 200 kb, in bp) | β (SE) P (CC)a | β (SE) P (MA1) | β (SE) P (MA2) |
rs10424198 | 19:17354824-17461934 | 19:17409671_C_T | − 0.262 (0.034) p = 1.40E−14 | – | Intronic | ABHD8, ANKLE1, ANO8, BABAM1, DDA1, GTPBP3, MRPL34, NR2F6, PLVAP, USHBP1 | ABHD8 | − 0.326 (0.193) p = 0.095 | − 0.010 (0.017) p = 0.556 | 0.002 (0.022) p = 0.911 |
UKBS (males) (N = 1333) | ||||||||||
rsID | Cluster | chr:pos_nonEA_EA | β (SE) P | β (SE) P (Proxy) | Location | Nearby genes | Lead SNP locus (or distance to genes within 200 kb, in bp) | β (SE) P (CC) | β (SE) P (MA1) | β (SE) P (MA2) |
rs11687359 | 2:1969703-1969704 | 2:1969704_G_A | 0.401 (0.078) p = 2.94e−07 | – | Intronic | MYT1L | MYT1L | 0.362 (0.080) p = 6.52e−06 | 0.006 (0.032) p = 0.845 | 0.043 (0.041) p = 0.286 |
rs13070764 | 3:73309902-73310337 | 3:73309903_G_A | − 0.497 (0.099) p = 5.84e−07 | – | Intergenic | . | PPP4R2 (dist = 194,892), PDZRN3 (dist = 121,678) | − 0.509 (0.100) p = 4.15e−07 | 0.100 (0.043) p = 0.020 | 0.098 (0.060) p = 0.101 |