Skip to main content

Table 3 Association of genetic ancestry (categorical variable)a with CRC status by age at recruitment

From: Association of genetic ancestry with colorectal tumor location in Puerto Rican Latinos

Ancestry

OR< 60 years

OR≥ 60 years

 

ORunadjusted

ORadjustedb

ORadjustedc

ORunadjusted

ORadjustedb

ORadjustedc

European ancestry

  ≤ (0.63)

1.0

  

1.0

  

  > (0.63)

0.91 (0.63–1.31)

0.85 (0.49–1.48)

0.94 (0.53–1.67)

0.95 (0.62–1.47)

0.95 (0.51–1.78)

0.97 (0.51–1.86)

African ancestry

  ≤ (0.18)

1.0

  

1.0

  

  > (0.18)

1.14 (0.79–1.63)

1.11 (0.64–1.92)

1.07 (0.60–1.91)

1.18 (0.76–1.83)

1.25 (0.67–2.35)

1.32 (0.70–2.52)

Amerindian ancestry

  ≤ (0.17)

1.0

  

1.0

  

  > (0.17)

1.35 (0.94–1.94)

1.39 (0.79–2.43)

1.31 (0.73–2.34)

1.00 (0.65–1.55)

0.76 (0.41–1.40)

0.75 (0.40–1.40)

  1. aDichotomous variables were analyzed using the median value of each ancestry marker among controls as a cut-off
  2. bPOR’s adjusted by age at recruitment, gender, education, and family history of CRC
  3. cPOR’s adjusted by age at recruitment, gender, education, and family history of CRC, ever smoked, and current drinking
  4. dCategorical variables were categorized into quartiles and treated as continuous variables to measure the variation in risk per 25% increase of each ancestry marker
Back to article page

Human Genomics

ISSN: 1479-7364