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Table 2 Genotype association between subjects

From: Association of HTRA1 and ARMS2 gene polymorphisms with response to intravitreal ranibizumab among neovascular age-related macular degenerative subjects

Gene variant W/M Subjects WW WM MM P valuea W (%) M (%) P valuea HWEb OR (95% CI)
           χ 2 P  
ARMS2 rs10490924 G/T nAMD 21 (14.5) 57 (39.3) 67 (46.2)   34.1 65.9   2.293 0.318 2.44
   Controls 46 (31.7) 70 (48.3) 29 (20.0) < 0.001* 55.9 44.1 < 0.001* 0.068 0.966 (1.75–3.42)
HTRA1 rs11200638 G/A nAMD 19 (13.1) 47 (32.4) 79 (54.5)   29.3 70.7   6.823 0.033 1.52
   Controls 15 (10.3) 82 (56.6) 48 (33.1) < 0.001* 38.6 61.4 0.018* 5.386 0.068 (1.07–2.15)
  1. Data are presented as percentages in parentheses
  2. M risk allele, W non-risk allele, OR odds ratio, CI confidence interval, HWE Hardy-Weinberg equilibrium
  3. *Significant P value, P < 0.05
  4. aChi-square test
  5. bχ2 goodness-of-fit test