Fig. 2From: Studies of liver tissue identify functional gene regulatory elements associated to gene expression, type 2 diabetes, and other metabolic diseasesUCSC Genome browser view of the AS-SNPs rs655185 and rs541091 (yellow) which are in high LD with the T2D-associated GWAS SNP rs622217 (cyan). The histone modification tracks represent the peaks called for the ChIP-seq of H3K4me3 performed in the liver (black) and the HepG2 signal from the ENCODE project (pink trace) as a comparison. Transcription factor binding sites (TFBSs) from ChIP-seq data from the ENCODE project for HepG2 and other cell lines. In the bottom insert, eQTL box plots from the GTEx project for the three SNPs with rank-normalized gene expression in liver tissue as a function of the different genotypesBack to article page