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Table 4 Multiple linear regression model of adjusted associations of demographic factors, H. pylori sero-status, and serological evidence of atrophic gastritis with leukocyte telomere length (kb)

From: Helicobacter pylori infection, serum pepsinogens as markers of atrophic gastritis, and leukocyte telomere length: a population-based study

  Beta coefficient (95% CI) p value
Sex
 Males − 0.08 (− 0.15, − 0.01) 0.032
 Females Reference  
Age, years
 27–34 Reference  
 35–44 − 0.19 (− 0.31, − 0.06) 0.003
 45–54 − 0.39 (− 0.51, − 0.26) < 0.001
 55–64 − 0.56 (− 0.69, − 0.44) < 0.001
 65–78 − 0.76 (− 0.89, − 0.64) < 0.001
Religiosity
 Religious − 0.07 (− 0.14, 0.01) 0.078
 Traditional/secular Reference  
H. pylori sero-status/atrophic gastritis*
H. pylori negative no atrophic gastritis Reference  
H. pylori positive no atrophic gastritis 0.05 (− 0.06, 0.16) 0.3
H. pylori positive plus atrophic gastritis 0.16 (− 0.03, 0.35) 0.10
Past H. pylori infection (IgG sero-negatives) plus atrophic gastritis − 0.21 (− 0.41, − 0.001) 0.049
  1. CI confidence intervals; IgG immunoglobulin G
  2. *Atrophic gastritis was defined as serum pepsinogen (PG) I < 30 μg/L or PGI:PGII < 3.0
  3. Model summary: adjusted R2 = 0.198, degrees of freedom = 9, (F statistic = 26.24), p < 0.001
  4. Adjusted for the variables in the table