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Table 1 List of liquid biopsy companies

From: Next-generation sequencing in liquid biopsy: cancer screening and early detection

Company

Product/study

Usage/aim

Reference

Grail

The SUMMIT Study

Evaluating a blood test designed to detect multiple types of cancer, including lung cancer

[35]

Guardant 360

Lunar-2

Early cancer detection among higher-risk asymptomatic individuals

[36]

Freenome

Screening test

Using AI-based algorithm for early detection of colorectal cancer and precancerous lesions known as advanced adenomas

[37]

Biocept

Target Selectorâ„¢ ctDNA EGFR Kit

EGFR mutation detection

[38]

Inivata

InVisionSeqâ„¢ and InVisionFirstâ„¢- Lung

Around 40 biomarkers (including mutations, CNV, SNV, fusions, indels) panel for advanced cancers molecular profiling, monitoring, and diagnosis

[39]

Cynvenio

The LiquidBiopsy® Platform

NGS-based techniques to detect mutations in as few as 1 target cell per mL/blood

[40]

CellMaxLife

FirstSightCRCâ„¢

Using circulating tumor cells for colorectal cancer, adenomas, and colorectal cancer screening and profiling

[41]

Exosomedx

Exosome-based biomarker tests*

Diagnosing non-small cell lung cancer and prostate cancer

[42]

Biodesix

GeneStrat® test

Providing blood-based mutation results of EGFR, ALK, ROS1, RET, BRAF, and KRAS for cancer diagnosis

[43]

Personal Genome Diagnostics

PlasmaSELECTâ„¢ -R 64

Cancer diagnosis using NGS with 64 Genes panel

[44]

  1. *Exosomes are extracellular vesicles (EVs) produced by cells. They contain RNA, proteins, lipids, and metabolites that are reflective of their origins [45]