Fig. 2
From: Novel analytical methods to interpret large sequencing data from small sample sizes
Overview of the two statistical strategies to highlight gene and polymorphisms most likely to be associated with IM resistance. First, either all polymorphisms or only polymorphisms with variant causing protein alterations can be selected. Second, two analyses can be performed. The FCA and HCPC method will display the polymorphisms individually on a two-dimensional graph according to VAFs. The simulation and RP will permit to rank genes according to VAFs (mean of VAFs per gene or sum divided by the size of the gene)