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Table 4 The association of the rs2151280 with lung cancer risks and NSCLC in female and male population

From: Association between polymorphism in CDKN2B-AS1 gene and its interaction with smoking on the risk of lung cancer in a Chinese population

GenotypingLung cancer Non-small-cell lung cancer 
 Controls (%)Cases (%)OR (95%CI)P valueORª (95%CI)Pª valueCases (%)OR (95%CI)P valueORª (95%CI)Pª value
Female           
TT104 (37.1)102 (40.5)1.00 (ref)   73 (37.8)1.00 (ref)   
TC123 (43.9)122 (48.4)1.011 (0.698–1.465)0.9530.984 (0.676–1.434)0.93597 (50.3)1.124 (0.753–1.677)0.5691.109 (0.740–1.661)0.616
CC53 (18.9)28 (11.1)0.539 (0.316–0.918)0.0230.533 (0.310–0.916)0.02323 (11.9)0.618 (0.348–1.097)0.1000.606 (0.339–1.081)0.090
CC+TC vs TT 0.869 (0.613–1.232)0.4310.850 (0.596–1.211)0.368 0.971 (0.665–1.419)0.8800.957 (0.653–1.402)0.822
CC vs TC+TT 0.535 (0.327–0.877)0.0130.538 (0.326–0.888)0.015 0.579 (0.342–0.983)0.0430.572 (0.335–0.975)0.040
T allele331 (59.1)326 (64.7)1.00 (ref)   243 (63.0)1.00 (ref)   
C allele229 (40.9)178 (35.3)0.789 (0.616–1.012)0.062  143 (37.0)0.851 (0.652–1.110)0.234  
Male           
TT99 (37.8)105 (41.2)1.00 (ref)    1.00 (ref)   
TC132 (50.4)122 (47.8)0.871 (0.603–1.260)0.4640.929 (0.570–1.515)0.76980 (40.0)0.928 (0.626–1.375)0.7101.078 (0.624–1.862)0.788
CC31 (11.8)28 (11.0)0.852 (0.477–1.521)0.5870.724 (0.336–1.558)0.40899 (49.5)0.838 (0.448–1.570)0.5820.743 (0.315–1.752)0.497
CC+TC vs TT 0.868 (0.610–1.235)0.4310.886 (0.555–1.4130)0.61121 (10.5)0.911 (0.625–1.329)0.6281.004 (0.596–1.692)0.989
CC vs TC+TT 0.919 (0.534–1.582)0.7610.753 (0.367–1.545)0.440 0.874 (0.486–1.573)0.6540.713 (0.320–1.590)0.408
T allele330 (63.0)332 (65.1)1.00 (ref)   259 (64.8)1.00 (ref)   
C allele194 (37.0)178 (34.9)0.912 (0.707–1.176)0.477  141 (35.2)0.926 (0.706–1.214)0.579  
  1. OR odds ratio, CI confidence interval, NSCLC non-small-cell lung cancer
  2. aAdjusted for age, gender, and smoking
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