Table 7 Relationship of interaction between rs2151280 and smoking with lung cancer risk and NSCLC
| Â | Controls (%) | Smoking | Â | Lung Cancer | Â | Non-small cell lung cancer | Â | Â | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|  |  |  | Cases (%) | OR (95%CI) | P value | ORª (95%CI) | Pa value | Cases (%) | OR (95%CI) | P value | ORª (95%CI) | Pa value |
CC | 75 (13.8) | Never | 31 (6.1) | 1.00 (ref) | Â | Â | Â | 25 (6.4) | 1.00 (ref) | Â | Â | Â |
TC+TT | 401 (74.0) | Never | 259 (51.1) | 1.563 (1.000–2.443) | 0.050 | 1.659 (1.056–2.606) | 0.028 | 194 (49.4) | 1.451 (0.894–2.355) | 0.131 | 1.559 (0.956–2.542) | 0.075 |
CC | 9 (1.7) | Ever | 25 (4.9) | 6.72 (2.818–16.029) | < 0.001 | 9.392 (3.849–22.914) | < 0.001 | 19 (4.8) | 6.333 (2.541–15.784) | < 0.001 | 8.42 (3.296–21.510) | < 0.001 |
TC+TT | 57 (10.5) | Ever | 192 (37.9) | 8.149 (4.882–13.604) | < 0.001 | 11.442 (6.626–19.761) | < 0.001 | 155 (39.4) | 8.158 (4.73–14.07) | < 0.001 | 10.905 (6.100–19.495) | < 0.001 |