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Fig. 2 | Human Genomics

Fig. 2

From: Copy number of 8q24.3 drives HSF1 expression and patient outcome in cancer: an individual patient data meta-analysis

Fig. 2

Copy number alteration of HSF1 drives HSF1 expression in cancers. a Distribution of HSF1 copy number alteration per different cancer types. Numbers in brackets indicate the number of patient samples per cancer type. b Pie charts of HSF1 CNA as a function of the HSF1 quartile expression per histopathological cancer types. Color annotations are described in the legend. Each pie chart displays the number of tumors analyzed and the median value of HSF1 for all samples in the category. Tumors having both CNA data and HSF1 were included. Abbreviations: N, number of samples; deep deletion, − 2 copies; shallow deletion, − 1 copy, diploid is the reference with normal HSF1 copy number; gain, + 1 copy; amplification, + 2, or more copies

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