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Table 3 Crude Cox regression models between chromosomal inversions and disease-free survival

From: Common polymorphic inversions at 17q21.31 and 8p23.1 associate with cancer prognosis

Tumorinv8p23.1inv17q21.31
Std-StdStd-InvInv-Invp valueStd-StdStd-InvInv-Invp value
Lung10.78 (0.61–1)0.050.88 (0.67–1.16)0.37
Lung210.82 (0.52–1.28)0.82 (0.52–1.28)0.38110.49 (0.2–1.2)0.12
Liver111.01 (0.61–1.68)0.9611.13 (0.74–1.74)1.13 (0.74–1.74)0.57
Colorectal10.86 (0.51–1.44)0.86 (0.51–1.44)0.5611.67 (1.1–2.53)11.57 × 10−2
Stomach110.79 (0.44–1.4)0.4210.98 (0.57–1.68)10.93
Breast10.66 (0.41–1.04)10.08112.01 (0.81–4.99)0.13
  1. The results are for the best genetic model for each inversion in each tumor. Associations in italics were nominally significant (p value < 0.05). In the additive model, HR corresponds to each inverted allele. For the other models, HR was computed using Std-Std as the reference
  2. Lung1 LUAD (lung adenocarcinoma), Lung2 LUSC (lung squamous cell carcinoma), Liver LIHC (liver hepatocellular carcinoma), Colorectal COAD + READ (colon adenocarcinoma), stomach: STAD (stomach adenocarcinoma), Breast BRCA (breast invasive carcinoma)