Genetic variants of VEGFR-1 gene promoter in acute myocardial infarction

Table 1 Genetic variants in the VEGFR-1 gene promoter identified in AMI patients and controls

DSVs and SNPs	Genotype	Location^a	Controls (n = 414)	AMI (n = 386)	P value
g.28495805C>T (rs111458691)	CT	− 677 bp	0	1	–
g.28495796G>T	GT	− 668 bp	0	1	–
g.28495678G>A	GA	− 550 bp	1	0	–
g.28495538C>T (rs17086747)	CC	− 410 bp	388	357	0.574
	CT		26	28
	TT		0	1
g.28495527G>A (rs117031451)	GG	− 399 bp	380	360	0.748
	GA		33	25
	AA		1	1
g.28495445G>T	GT	− 317 bp	0	1	–
g.28495412C>T (rs36204411)	CC	− 284 bp	388	357	0.574
	CT		26	28
	TT		0	1
g.28495356G>A	GA	− 228 bp	1	0	–
g.28495341A>G	AG	− 213 bp	0	1	–
g.28495138G>C	GC	− 10 bp	0	1	–
g.28495135 G>C (rs17086745)	GG	− 7 bp	388	357	0.574
	GC		26	28
	CC		0	1
g.28495029G>T	GT	+ 99 bp	1	1	1.000
g.28495028C>A	CA	+ 100 bp	1	1	1.000
g.28494902C>T (rs55927955)	CC	+ 226 bp	355	343	0.162
	CT		58	43
	TT		1	0
g.28494900G>A	GA	+ 228 bp	0	1	–
g.28494895G>T	GT	+ 233 bp	1	1	1.000

^aDSVs are located upstream (−) and downstream (+) to the transcription start site at 28495128 of VEGFR-1 gene (NC_000013.11). AMI acute myocardial infarction, DSV DNA sequence variant, − not applicable

ISSN: 1479-7364