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Fig. 5 | Human Genomics

Fig. 5

From: Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting BMP7

Fig. 5

A proposed schematic diagram of miR-542-3p regulating the osteogenic transition of VSMCs in aging rats. MiR-542-3p expression is downregulated in oVSMCs. As a target of MiR-542-3p, the expression of BMP7 is upregulated which results in the osteogenic differentiation of VSMCs, suggesting the role of miR-542-3p in the vascular osteogenic transition in aging rat

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