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Table 5 Differences in various clinical parameters according to micro RNA polymorphisms in control women

From: Associations between microRNA (miR-25, miR-32, miR-125, and miR-222) polymorphisms and recurrent implantation failure in Korean women

Control

Genotypes

Age (years)

BMI (kg/m2)

Live births (n)

Mean gestational age (weeks)

PT (s)

aPTT (s)

PLT (103/μl)

Folate (mg/ml)

Total cholesterol (mg/dl)

BUN (mg/dl)

Creatinine (mg/dl)

E2 (Basal)

FSH (mU/L)

LH (mU/L)

Mean ± SD (228)

Mean ± SD (104)

Mean ± SD (74)

Mean ± SD (96)

Mean ± SD (47)

Mean ± SD (77)

Mean ± SD (187)

Mean ± SD (14)

Mean ± SD (9)

Mean ± SD (30)

Mean ± SD (30)

Mean ± SD (109)

Mean ± SD (109)

Mean ± SD (106)

miR-25 T>C

 TT

33.8 ± 3.30

21.7 ± 3.41

1.7 ± 0.62

39.1 ± 1.75

11.7 ± 3.62

30.9 ± 4.76

243.8 ± 59.58

16.1 ± 10.79

188.4 ± 40.62

8.0 ± 1.74

0.7 ± 0.09

27.0 ± 15.02

8.1 ± 2.89

3.1 ± 1.55

 TC

33.8 ± 3.20

22.0 ± 2.91

2.0 ± 0.37

39.4 ± 1.47

10.4 ± 0.98

30.5 ± 4.31

238.0 ± 60.87

13.1 ± 4.61

373.0 ± 52.33

8.1 ± 2.34

0.7 ± 0.05

24.0 ± 14.38

8.5 ± 2.90

4.0 ± 2.17

 CC

33.3 ± 2.52

N/A

N/A

N/A

N/A

N/A

297.7 ± 57.76

N/A

N/A

N/A

N/A

22.2 ± 7.87

7.2 ± 1.26

5.6 ± 1.17

 P value

0.974

0.707

0.077

0.465

0.208

0.739

0.246

0.563

0.001

0.915

0.316

0.608

0.681

0.006

miR-32 C>A

 CC

33.7 ± 3.28

21.7 ± 3.33

1.8 ± 0.56

39.5 ± 1.54

11.4 ± 3.24

30.9 ± 4.60

242.0 ± 61.76

15.1 ± 9.34

235.9 ± 102.77

8.3 ± 1.79

0.7 ± 0.07

27.0 ± 14.82

8.0 ± 2.72

3.2 ± 1.67

 CA

33.9 ± 3.30

22.0 ± 3.34

1.9 ± 0.70

37.8 ± 1.86

10.1 ± 1.84

29.3 ± 4.75

249.8 ± 51.16

14.9

207.0 ± 31.11

6.9 ± 1.66

0.7 ± 0.10

24.0 ± 14.35

8.9 ± 3.34

3.8 ± 2.11

 AA

35.0

22.9

1.0

39.5 ± 0.71

11.4

35.7

250.5 ± 67.18

N/A

N/A

N/A

N/A

11.1

5.7

4.1

 P value

0.809

0.882

0.310

0.002

0.720

0.341

0.796

0.987

0.718

0.092

0.316

0.430

0.291

0.296

miR-125a C>T

 CC

33.8 ± 3.39

21.7 ± 3.19

1.8 ± 0.61

39.2 ± 1.75

11.5 ± 3.59

30.5 ± 4.09

240.8 ± 60.91

15.1 ± 9.91

238.2 ± 86.80

7.8 ± 1.84

0.7 ± 0.09

26.5 ± 14.86

8.0 ± 2.43

3.3 ± 1.78

 CT

33.6 ± 2.83

21.4 ± 3.70

1.6 ± 0.51

39.2 ± 1.52

10.9 ± 0.56

31.5 ± 6.91

247.1 ± 58.14

15.0 ± 5.62

212.0 ± 115.31

9.3 ± 1.33

0.7 ± 0.04

25.0 ± 14.57

8.5 ± 3.83

3.4 ± 1.78

 TT

33.3 ± 3.61

23.7 ± 4.04

1.8 ± 0.50

38.3 ± 0.87

10.4 ± 0.76

32.2 ± 0.67

276.5 ± 45.14

0.0

N/A

N/A

N/A

37.5 ± 12.09

8.0 ± 2.97

2.0 ± 0.42

 P value

0.863

0.460

0.573

0.525

0.791

0.673

0.330

0.988

0.711

0.098

< 0.001

0.506

0.755

0.554

miR-222 G>T

 GG

33.6 ± 3.17

21.5 ± 3.24

1.7 ± 0.58

39.0 ± 1.45

11.0 ± 1.90

31.2 ± 5.25

243.5 ± 58.97

17.1 ± 11.22

177.4 ± 44.07

8.4 ± 1.65

0.7 ± 0.06

25.6 ± 14.52

8.0 ± 2.38

3.4 ± 1.54

 GT

33.9 ± 3.40

22.0 ± 3.47

1.8 ± 0.61

39.5 ± 1.74

10.8 ± 0.72

29.8 ± 3.38

240.9 ± 62.74

12.3 ± 4.13

294.5 ± 95.55

7.8 ± 1.80

0.6 ± 0.08

28.1 ± 15.28

8.4 ± 3.54

3.2 ± 2.08

 TT

34.4 ± 3.44

22.0 ± 3.53

2.2 ± 0.45

38.9 ± 2.93

16.5 ± 11.14

31.1 ± 2.72

254.2 ± 56.51

N/A

N/A

4.2

0.6

22.6 ± 13.98

7.9 ± 2.55

3.3 ± 1.76

 P value

0.541

0.778

0.227

0.144

0.946

0.479

0.751

0.561

0.050

0.059

0.005

0.531

0.778

0.845

  1. Italicized text indicates significant P values
  2. BMI, body mass index; PT, prothrombin time; aPTT, activated partial thromboplastin time; PLT, platelets; BUN, blood urea nitrogen; E2, estradiol; TSH, thyroid stimulating hormone; FSH, follicle stimulating hormone; LH, luteinizing hormone; WBC, white blood cell; Hgb, hemoglobin
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Human Genomics

ISSN: 1479-7364