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Table 1 Clinical characteristic of pregnant women undergoing NIPT

From: Noninvasive prenatal testing for chromosome aneuploidies and subchromosomal microdeletions/microduplications in a cohort of 42,910 single pregnancies with different clinical features

Gestational age at NIPT (weeks)No./N = 42910Rate (%)
 12~15+6553512.90
 16~19+62475957.70
 20~23+61051324.50
 24~26+621034.90
Clinical featuresNo.Rate (%)
 Fetal structural abnormalities by B-ultrasound2020.47
 Increased NT574913.4
 Othera120.03
 High risk of serological screening23185.40
 Critical risk of serological screening1586336.97
 Advance maternal age (≥ 35 years)1074225.03
 No clinical indications802418.70
  1. aPatients with interventional surgery contraindications: reoperative infection, placenta previa, placental bleeding, poor pregnancy history