Noninvasive prenatal testing for chromosome aneuploidies and subchromosomal microdeletions/microduplications in a cohort of 42,910 single pregnancies with different clinical features

Table 1 Clinical characteristic of pregnant women undergoing NIPT

Gestational age at NIPT (weeks)	No./N = 42910	Rate (%)
12~15⁺⁶	5535	12.90
16~19⁺⁶	24759	57.70
20~23⁺⁶	10513	24.50
24~26⁺⁶	2103	4.90
Clinical features	No.	Rate (%)
Fetal structural abnormalities by B-ultrasound	202	0.47
Increased NT	5749	13.4
Other^a	12	0.03
High risk of serological screening	2318	5.40
Critical risk of serological screening	15863	36.97
Advance maternal age (≥ 35 years)	10742	25.03
No clinical indications	8024	18.70

^aPatients with interventional surgery contraindications: reoperative infection, placenta previa, placental bleeding, poor pregnancy history

ISSN: 1479-7364