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Fig. 3 | Human Genomics

Fig. 3

From: Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease

Fig. 3

Ethanol effects on RNA expression levels via RNA sequencing analysis. a Pipeline for identification of NMN-dependent and NMN-independent ethanol effects on RNA expression levels. b RNA expression differences across the treatment (NMN and ethanol) combinations for genes with NMN-dependent ethanol effects. Each row represents a gene with a significant ethanol effect (FDR < 0.05) that was classified as NMN-dependent (differential ethanol p < 0.05; 437 genes). Expression levels are shown as the ratio of average expression level in each treatment combination (columns) to the average expression in the Control Saline group. Expression levels were log base 2 transformed prior to analyses and graphing. Values in the key have be back transformed to increase interpretability

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