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Table 2 Number of common (MAF > 0.10), intermediate frequency (MAF 0.05–0.10), low frequency (0.01–0.05) and rare variants (MAF < 0.01) for each assessed drug

From: Delineating significant genome-wide associations of variants with antipsychotic and antidepressant treatment response: implications for clinical pharmacogenomics

Drug

Common (N genes or SNPs)

Interm (N genes or SNPs)

Low freq (N genes or SNPs)

Rare (N genes or SNPs)

No1000 G MAF (N genes or SNPs)

Total (per drug)

Aripiprazole

2

-

-

-

-

2

Bupropion

6

-

5

8

2

21

Clozapine

35

7

16

11

8

77

Citalopram

7

2

7

8

7

31

Duloxetine

1

-

-

-

1

2

Escitalopram

3

1

1

8

4

17

Haloperidol

6

1

-

-

1

8

Iloperidone

5

1

-

-

-

6

Ketamine

13

2

-

-

4

19

Lurasidone

11

-

-

-

2

13

Olanzapine

10

3

-

-

2

15

Oxcarbazepine

4

1

2

-

-

7

Paliperidone

56

22

34

56

24

192

Perphenazine

11

1

3

-

1

16

Quetiapine

14

1

1

-

2

18

Risperidone

15

-

1

-

4

20

Sertraline

-

1

1

-

-

2

Venlafaxine

11

1

2

1

3

18

Ziprasidone

8

1

-

1

-

10

Total (per MAF)

218

45

73

93

65

 
  1. The number of SNPs counted is equal to the number of genes as duplicates of the same drug–SNP correlations were removed
  2. interm intermediate, low freq low frequency, MAF minor allele frequency
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Human Genomics

ISSN: 1479-7364