Table 11 Results for GPC6, rs17267815. Corrected P values using the Benjimini-Hochberg (PBH) and Bonferroni (PBon) methods are presented below the uncorrected P value
| Â | GPC6 | rs17267815 | |||||||
|---|---|---|---|---|---|---|---|---|---|
Polymorphism | Genotypes | Â | Alleles | ||||||
Group | AA (%) | AG (%) | GG (%) | P (PBH, PBon) | HWE | A (%) | G (%) | P | OR (95% CI) |
MS total cases (n= 205) | 46 (22.4) | 105 (51.2) | 54 (26.4) | 0.0797 (0.213, 0.638) | 0.71 | 197 (48.1) | 213 (51.9) | 0.118 | 0.79 |
PP case (n= 54) | 10 (18.5) | 26 (48.2) | 18 (33.3) | 0.691 | Â | 46 (42.6) | 62 (57.4) | 0.925 | 0.98 |
SP case (n= 51) | 8 (15.7) | 29 (56.9) | 14 (27.4) | 0.161 | Â | 45 (51.7) | 42 (48.3) | 0.719 | 0.92 |
RR case (n= 100) | 28 (28.0) | 50 (50.0) | 22 (22.0) | 0.039 | Â | 106 (51.7) | 94 (48.3) | 0.017 | 0.64 |
Male (n= 45) | 14 (31.1) | 20 (44.4) | 11 (24.4) | 0.1436 | Â | 48 (53.3) | 42 (46.7) | 0.0386 | 0.51 |
Female (n= 160) | 32 (20.0) | 85 (53.1) | 43 (26.9) | 0.1154 | Â | 149 (46.6) | 171 (53.4) | 0.5095 | 0.89 |
Control (n= 145) | 31 (21.4) | 60 (41.4) | 54 (37.2) | Â | 0.069 | 205 (54.5) | 171 (45.5) | Â | Â |
HapMap CEU (%) | 26.5 | 54 | 19.5 | Â | Â | 53.5 | 46.5 | Â | Â |