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Table 12 Results for GPC6, rs9524260. Corrected P values using the Benjimini-Hochberg (PBH) and Bonferroni (PBon) methods are presented below the uncorrected P value

From: An investigation of genetic polymorphisms in heparan sulfate proteoglycan core proteins and key modification enzymes in an Australian Caucasian multiple sclerosis population

 

GPC6

rs9524260

Polymorphism

Genotypes

 

Alleles

Group

GG (%)

GA (%)

AA (%)

P

(PBH, PBon)

HWE

G (%)

A (%)

P

OR (95% CI)

MS total cases (n= 197)

76 (38.6)

90 (45.7)

31 (15.7)

0.236

(0.472, 1)

0.613

242 (61.4)

152 (38.6)

0.974

1.00

PP case (n= 53)

22 (41.5)

21 (39.6)

10 (18.9)

0.146

 

65 (61.3)

41 (38.7)

0.967

1.01

SP case (n= 50)

16 (32.0)

24 (48.0)

10 (20.0)

0.296

 

56 (56.0)

44 (44.0)

0.316

1.26

RR case (n= 94)

38 (40.4)

45 (47.9)

11 (11.7)

0.607

 

121 (64.4)

67 (35.6)

0.516

0.89

Control (n= 182)

63 (34.6)

98 (53.8)

21 (11.6)

 

0.064

224 (61.5)

140 (38.5)

  

HapMap CEU (%)

36.3

54.9

8.8

  

63.7

36.3

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