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Table 3 Genotype and allele frequencies of EXT-1 SNP (rs11546829) within the case-control MS population which is further subdivided into disease states. Corrected P values using the Benjimini-Hochberg (PBH) and Bonferroni (PBon) methods are presented below the uncorrected P value

From: An investigation of genetic polymorphisms in heparan sulfate proteoglycan core proteins and key modification enzymes in an Australian Caucasian multiple sclerosis population

 EXT1-829rs11546829
PolymorphismGenotypes Alleles
GroupGG (%)GA (%)AA (%)P(PBH, PBon)HWEG (%)A (%)POR (95% CI)
MS total cases (n= 176)80 (45.5)78 (44.3)18 (10.2)0.45 (0.72, 1)0.87238 (67.6)114 (32.4)0.750.95
PP case (n= 49)22 (44.9)22 (44.9)5 (10.2)0.67 66 (67.3)32 (32.7)0.870.96
SP case (n= 43)21 (48.8)19 (44.2)3 (7)0.45 61 (70.9)25 (29.1)0.440.81
RR case (n= 84)37 (44)37 (44)10 (12)0.72 111 (66.1)57 (51.4)0.941.02
Control (n= 134)63 (47)52 (38.9)19 (14.2)0.13178 (66.4)90 (33.6)
HapMap CEU (%)58.336.75  76.723.3  
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