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Table 5 Results by disease state for SDC1 SNP (rs1131351) and of the MS case-control population. Corrected P values using the Benjimini-Hochberg (PBH) and Bonferroni (PBon) methods are presented below the uncorrected P value

From: An investigation of genetic polymorphisms in heparan sulfate proteoglycan core proteins and key modification enzymes in an Australian Caucasian multiple sclerosis population

 SDC 1rs113151
PolymorphismGenotypes Alleles
GroupGG (%)GC (%)CC (%)P
(PBH, PBon)
HWEG (%)C (%)POR (95% CI)
MS total cases (n= 160)31 (19.4)83 (51.9)46 (28.8)0.02
(0.08, 0.16)
0.55145 (45.3)175 (54.7)0.0041.59
PP case (n= 45)8 (17.8)24 (53.3)13 (28.9)0.11 40 (44.4)50 (55.6)0.041.65
SP case (n= 39)8 (20.5)19 (48.7)12 (30.8)0.15 35 (44.9)43 (55.1)0.061.62
RR case (n= 76)15 (19.7)40 (52.6)21 (27.6)0.09 70 (46.1)82 (53.9)0.031.55
Male (n= 31)7 (22.6)17 (54.8)7 (22.6)0.58 31 (50)31 (50)0.321.32
Female (n= 129)24 (18.6)66 (51.2)39 (30.2)0.01 114 (44.2)144 (58.8)0.0031.67
Total control (n= 145)46 (31.7)73 (50.3)26 (17.9)0.75165 (56.9)125 (43.1) 
HapMap CEU (%)503119  65.534.5  
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