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Table 6 Female results by disease state for SDC1 SNP (rs1131351)

From: An investigation of genetic polymorphisms in heparan sulfate proteoglycan core proteins and key modification enzymes in an Australian Caucasian multiple sclerosis population

 

SDC1

rs1131351

Polymorphism

Genotypes

Alleles

Group

GG (%)

GC (%)

CC (%)

P

G (%)

C (%)

P

OR (95% CI)

Female MS case

PP (n= 31)

3 (9.68)

17 (54.8)

11 (35.5)

0.02

23 (37.1)

39 (62.9)

0.005

2.24

SP (n= 28)

7 (25)

13 (46.4)

8 (28.6)

0.41

27 (48.2)

29 (51.8)

0.23

1.42

RR (n= 70)

14 (20)

36 (51.4)

20 (28.6)

0.09

64 (45.7)

76 (54.3)

0.03

1.57

Total control (n= 145)

46 (31.7)

73 (50.3)

26 (17.9)

–

165 (56.9)

125 (43.1)

–

–

HapMap CEU (%)

50

31

19

 

65.5

34.5

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