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Table 3 NIPT results in total samples and AMA women samples

From: Clinical performance of non-invasive prenatal served as a first-tier screening test for trisomy 21, 18, 13 and sex chromosome aneuploidy in a pilot city in China

NIPTTotal samplesAMA women
T21T18T13SCAsTotalT21T18T13SCATotal
Total positive cases873122141281401372989
Frequency1/4931/13851/19511/3041/1531/2281/7031/13051/3151/103
TP511725112126411344
FP14101857994141019
PPV`78.46%62.96%10.00%47.22%55.00%86.67%80.00%20.00%56.52%69.84%
  1. TP true positive, FP false-positive, PPV positive predictive value, T21 trisomy 21, T18 trisomy 18; T13 trisomy 13; SCAs sex chromosomal aneuploidies, AMA advanced maternal age