Table 3 Significantly enriched pathway
Gene set name[#Genes(K)] | Description | #Genes in Overlap(k) | p value | FDR q value |
|---|---|---|---|---|
REACTOME_INTERFERON_GAMMA_SIGNALING[63] | Interferon gamma signaling | 5 | 2.61E−09 | 2.81E−06 |
KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION[89] | Antigen processing and presentation | 5 | 1.52E−08 | 8.16E−06 |
KEGG_ALLOGRAFT_REJECTION[38] | Allograft rejection | 4 | 3.55E−08 | 1.28E−05 |
KEGG_GRAFT_VERSUS_HOST_DISEASE[42] | Graft-versus-host disease | 4 | 5.35E−08 | 1.40E−05 |
KEGG_TYPE_I_DIABETES_MELLITUS[44] | Type I diabetes mellitus | 4 | 6.51E−08 | 1.40E−05 |
KEGG_CELL_ADHESION_MOLECULES_CAMS[134] | Cell adhesion molecules (CAMs) | 5 | 1.19E−07 | 2.13E−05 |
KEGG_AUTOIMMUNE_THYROID_DISEASE[53] | Autoimmune thyroid disease | 4 | 1.40E−07 | 2.15E−05 |
REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE[14] | Translocation of ZAP-70 to immunological synapse | 3 | 2.21E−07 | 2.97E−05 |
REACTOME_INTERFERON_SIGNALING[159] | Interferon signaling | 5 | 2.78E−07 | 3.32E−05 |
REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS[16] | Phosphorylation of CD3 and TCR zeta chains | 3 | 3.39E−07 | 3.66E−05 |