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Table 2 Genotypic and allelic distributions in the case and control groups

From: Exploration of CYP21A2 and CYP17A1 polymorphisms and preeclampsia risk among Chinese Han population: a large-scale case-control study based on 5021 subjects

  

Cases, N = 2002

Controls, N = 3019

χ2

P

Pc

OR (95% CI)

rs4409766

 Genotypes

TT

1018 (50.85)

1509 (49.98)

2.518

0.284

 

CT

826 (41.25)

1233 (40.84)

   

CC

158 (7.90)

277 (9.18)

   

 Alleles

T

2862 (71.47)

4251 (70.40)

1.345

0.246

0.984

1.054 (0.965~1.151)

C

1142 (28.43)

1787 (29.60)

   

rs1004467

 Genotypes

CC

259 (12.94)

419 (13.90)

1.424

0.491

 

CT

920 (45.95)

1401 (46.40)

   

TT

823 (41.11)

1199 (39.70)

   

 Alleles

C

1438 (35.91)

2239 (37.08)

1.414

0.234

0.936

0.951 (0.875~1.033)

T

2566 (64.09)

3799 (62.92)

   

rs3824755

 Genotypes

GG

856 (42.76)

1232 (40.81)

2.392

0.302

 

GC

908 (45.35)

1396 (46.24)

   

CC

238 (11.89)

391 (12.95)

   

 Alleles

G

2620 (65.43)

3860 (63.93)

2.386

0.122

0.488

0.936 (0.861~1.018)

C

1384 (44.57)

2178 (36.07)

   

rs2021783

 Genotypes

CC

1362 (68.03)

1936 (64.13)

8.151

0.017

0.068

 

CT

567 (28.32)

961 (31.83)

   

TT

73 (3.65)

122 (4.04)

   

 Alleles

C

3291 (82.19)

4833 (80.04)

7.201

0.007a

0.028a

1.151 (1.039~1.275)

T

713 (17.81)

1205 (19.96)

   
  1. Pc P value corrected by Bonferroni’s method
  2. aSignificant difference vs. controls