Table 3 Genotype and allele distributions in the mild/severe PE and control groups

From: Exploration of CYP21A2 and CYP17A1 polymorphisms and preeclampsia risk among Chinese Han population: a large-scale case-control study based on 5021 subjects

SNP		Control	Mild PE	χ²	P value	Pc	OR	95% CI	Severe PE	χ²	P value	Pc	OR	95% CI
	N	3019	454						1548
rs4409766	TT	1509	252						766
	CT	1233	170						656
	CC	277	32	5.508	0.064	0.256			126	1.879	0.651
	T	4251	674						2188
	C	1787	234	5.598	0.018	0.072	1.211	1.033–1.419	908	0.071	0.791		1.013	0.921–1.114
rs1004467	TT	1199	210						613
	CT	1401	192						728
	CC	419	52	7.330	0.026	0.104			205	0.390	0.823
	T	3799	612						1954
	C	2239	296	6.843	0.009^a	0.036^a	1.219	1.051–1.413	1142	0.034	0.855		1.008	0.922–1.103
rs3824755	GG	1232	215						641
	GC	1396	191						717
	CC	391	48	7.330	0.026	0.104			190	0.460	0.794
	G	3860	621						1999
	C	2178	287	6.869	0.009^a	0.036^a	1.221	1.051–1.418	1097	0.363	0.547		0.973	0.888–1.065
rs2021783	TT	122	12						61
	CT	961	132						435
	CC	1936	310	4.005	0.135	0.540			1052	6.982	0.030	0.120
	T	1205	156						557
	C	4833	752	3.862	0.049	0.196	1.202	1.000–1.444	2539	5.081	0.024	0.096	1.137	1.017–1.270

Pc P value corrected by Bonferroni’s method
^aSignificant difference vs. controls

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