Table 4 Genotype and allele distributions in the early-onset/late-onset PE and control groups

From: Exploration of CYP21A2 and CYP17A1 polymorphisms and preeclampsia risk among Chinese Han population: a large-scale case-control study based on 5021 subjects

		Control	Early-onset PE	χ²	P value	Pc	OR	95% CI	Severe PE	χ²	P value	Pc	OR	95% CI
	N	3019	937						1065
rs4409766	TT	1509	460						558
	CT	1233	405						421
	CC	277	72	2.896	0.235				86	2.195	0.334
	T	4251	1325						1537
	C	1787	549	0.062	0.803		1.015	0.905–1.137	593	2.226	0.136		1.087	0.974–1.213
rs1004467	TT	1199	372						451
	CT	1401	442						478
	CC	419	123	0.385	0.825				136	2.460	0.292
	T	3799	1186						1380
	C	2239	688	0.083	0.773		1.016	0.912–1.131	750	2.374	0.123		1.084	0.978–1.202
rs3824755	GG	1232	385						471
	GC	1396	445						463
	CC	391	107	1.587	0.452				131	3.789	0.150
	G	3860	1215						1405
	C	2178	659	0.511	0.475		0.961	0.863–1.071	725	2.843	0.092		1.093	0.986–1.213
rs2021783	TT	122	35						38
	CT	961	242						325
	CC	1936	660	12.986	0.002^a	0.008^a			702	1.272	0.529
	T	1205	312						401
	C	4833	1562	10.099	0.001^a	0.004^a	1.248	1.088–1.431	1729	1.274	0.259		1.138	0.948–1.219
	CT	961	242						325
	CC+TT	2058	695	12.183	0.000^a	0.000^a	0.746	0.632–0.880	740	0.631	0.427		1.063	0.914–1.237
	CC	1936	660						702
	CT+TT	1083	277	12.622	0.000^a	0.000^a	1.333	1.137–1.562	363	1.101	0.294		0.924	0.798–1.071

Pc P value corrected by Bonferroni’s method
^aSignificant difference

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