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Table 5 Laboratory-based examination of PE among different genotypes

From: Exploration of CYP21A2 and CYP17A1 polymorphisms and preeclampsia risk among Chinese Han population: a large-scale case-control study based on 5021 subjects

 

(1) TT

(2) CT

(3) CC

(1) vs. (2) vs. (3)

(1) vs. (2)

(1) vs. (3)

(2) vs. (3)

(1) + (2) vs. (3)

(1) vs. (2) + (3)

P

P

P

P

P

P

Age (years)

30.15 ± 6.13

29.99 ± 5.51

30.12 ± 5.50

0.894

0.817

0.962

0.644

0.679

0.917

Age of menarche (years)

13.55 ± 1.31

14.01 ± 1.09

14.00 ± 1.22

0.012a

0.027a

0.027a

0.999

0.458

0.003a

Number of abortion

0.617 ± 0.90

0.615 ± 0.95

0.619 ± 0.95

0.981

0.984

0.952

0.051

0.844

0.97

Gestational age at admission (weeks)

35.62 ± 3.07

35.64 ± 3.65

35.49 ± 3.44

0.700

0.963

0.768

0.411

0.399

0.845

Gestational age at delivery (weeks)

36.12 ± 2.89

36.17 ± 3.32

36.24 ± 3.00

0.893

0.372

0.353

0.169

0.653

0.791

Fetal birth weight (g)

2603 ± 975

2616 ± 952

2593 ± 926

0.895

0.910

0.931

0.638

0.647

0.979

Systolic blood pressure (mmHg)

160.28 ± 17.38

159.80 ± 17.84

159.41 ± 17.84

0.854

0.830

0.686

0.662

0.604

0.724

Diastolic blood pressure (mmHg)

103.78 ± 12.58

103.62 ± 13.11

104.37 ± 13.90

0.533

0.927

0.718

0.272

0.263

0.819

White blood cell (×109/l)

9.56 ± 2.81

9.70 ± 2.99

9.72 ± 3.08

0.910

0.704

0.666

0.927

0.835

0.672

Triglyceride (mmol/l)

3.82 ± 1.87

3.88 ± 1.69

3.91 ± 1.95

0.929

0.822

0.738

0.818

0.756

0.759

Total cholesterol (mmol/l)

6.69 ± 1.70

6.71 ± 1.95

6.72 ± 1.92

0.980

0.960

0.899

0.862

0.844

0.916

Urea nitrogen (mmol/l)

4.54 ± 1.77

4.49 ± 1.72

4.73 ± 2.00

0.048a

0.832

0.435

0.016a

0.009a

0.624

Creatinine (μmol/l)

61.69 ± 21.18

64.29 ± 25.48

65.39 ± 28.94

0.466

0.473

0.290

0.446

0.314

0.330

  1. aSignificant difference