Table 3 Genotype and allele frequencies of younger and older patients, and younger and older healthy controls

From: The haplotypes of various TNF related genes associated with scleritis in Chinese Han

SNP	Genotype/allele	Younger cases		Older cases		P value	Pc value	OR (95% CI)
SNP	Genotype/allele	n	Frequency	n	Frequency	P value	Pc value	OR (95% CI)
rs9494885	TT	213	0.845	261	0.861	0.592	NS	0.879 (0.548–1.409)
	TC	37	0.147	42	0.139	0.783	NS	1.069 (0.663–1.724)
	CC	2	0.008	0	0	0.120	NS	–
	T	463	0.919	564	0.931	0.048	NS	0.841 (0.538–1.316)
	C	41	0.081	42	0.069	0.048	NS	1.189 (0.760–1.860)
rs2230926	GG	1	0.004	1	0.003	0.900	NS	1.195 (0.074–19.206)
	GT	27	0.107	29	0.097	0.675	NS	1.126 (0.647–1.957)
	TT	224	0.889	271	0.900	0.662	NS	0.886 (0.514–1.572)
	G	29	0.058	31	0.051	0.658	NS	1.125 (0.668–1.893)
	T	475	0.942	571	0.949	0.658	NS	0.889 (0.528–1.497)
		Younger controls		Older controls		P value	Pc value	OR (95% CI)
		n	Frequency	n	Frequency	P value	Pc value	OR (95% CI)
rs9494885	TT	324	0.885	335	0.898	0.573	NS	0.875 (0.550–1.393)
	TC	42	0.115	36	0.097	0.420	NS	1.213 (0.758–1.943)
	CC	0	0	2	0.005	0.161	NS	–
	T	690	0.943	706	0.946	0.752	NS	0.931 (0.596–1.453)
	C	42	0.057	40	0.054	0.752	NS	1.074 (0.688–1.677)
rs2230926	GG	0	0	2	0.005	0.160	NS	–
	GT	29	0.081	21	0.058	0.217	NS	1.440 (0.805–2.575)
	TT	330	0.919	342	0.937	0.355	NS	0.765 (0.434–1.350)
	G	29	0.040	25	0.034	0.537	NS	1.187 (0.688–2.047)
	T	689	0.960	705	0.966	0.537	NS	0.843 (0.488–1.453)

Pc value P value with Bonferroni correction, CI Confidence interval, OR Odds ratio. Pc value < 0.05 was regarded to have statistical significance

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ISSN: 1479-7364

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