Table 4 Haplotype analysis for association of TNFAIP3 gene polymorphisms with scleritis
From: The haplotypes of various TNF related genes associated with scleritis in Chinese Han
|  | Haplotypea | Cases (%) | Controls (%) | χ2 | P value | Pc value | OR (95% CI) |
|---|---|---|---|---|---|---|---|
Scleritis | CGG | 57.95 (0.052) | 52.81 (0.037) | 3.922 | 0.048 | NS | 1.467 (1.002~2.149) |
TAT | 93.33 (0.085) | 95.70 (0.066) | 3.168 | 0.075 | NS | 1.390 (0.972~1.761) | |
TGT | 926.62 (0.839) | 1268.28 (0.878) | 7.307 | 0.007 | 0.021 | 0.717 (0.563~0.913) | |
Scleritis subgroups | |||||||
 Anterior scleritis | TGT | 593.56 (0.841) | 1268.28 (0.878) | 5.103 | 0.024 | NS | 0.729 (0.554~0.960) |
 Posterior scleritis | TGT | 229.34 (0.837) | 1268.28 (0.878) | 3.531 | 0.060 | NS | 0.695 (0.475~1.017) |
 Pan-scleritis | TGT | 53.00 (0.828) | 1268.28 (0.878) | 1.518 | 0.218 | NS | 0.659 (0.338~1.285) |
 Scleritis without systemic disease | TGT | 835.12 (0.840) | 1268.28 (0.878) | 7.072 | 0.008 | 0.024 | 0.715 (0.558~0.916) |
 Scleritis with systemic disease | TGT | 92.00 (0.836) | 1268.28 (0.878) | 1.777 | 0.183 | NS | 0.699 (0.412~1.187) |