Fig. 3From: Comprehensive assessments of germline deletion structural variants reveal the association between prognostic MUC4 and CEP72 deletions and immune response gene expression in colorectal cancer patientsThe frequency spectrum of DSVs in cancer and non-cancer subjects and germline cancer susceptibility gene analysis. a Bar plot of the top 10 DSV genes with significant odds ratios and p-adjusted values < 0.05 by the false discovery rate (FDR) in the cancer group and non-cancer group separately. The x-axis indicates the percentage of subjects who carry DSV genes, while the y-axis represents the DSV genes. b Heatmap of 57 DSV genes and clinical information. Genes with an odds ratio and p-adjusted value < 0.05 by the FDR were selected. The clinical information includes sex, age, and FCH. c Bar plot of 26 DSV genes intersected in 565 germline cancer susceptibility genes in cancer and non-cancer subjects. The x-axis indicates the well-known cancer susceptibility genes, and the y-axis indicates the frequency of the genes in cancer and non-cancer subjects. FANCA, POLD1, and STK11 gene deletions occurred only in the cancer groupBack to article page