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Table 1 List of statistically significant over-expressed segments (q<0.05) in trisomy 21 (T21) vs normal control blood cell transcriptome map

From: The transcriptome profile of human trisomy 21 blood cells

Chr

Location

Segment start

Segment end

Expression ratio

Genes

Chr21

21q22.2-q22.3

41,250,001

41,750,000

4.16

MX2, MX1, RIPK4

Chr21

21q22.3

44,000,001

44,500,000

4.11

PWP2, TRPM2, TSPEAR

Chr22

22q11.22

21,750,001

22,250,000

3.65

IGLV4-69, IGLV8-61, IGLV10-54

Chr10

10q23.31

89,000,001

89,500,000

2.78

IFIT2, IFIT3, IFIT1

  1. Segments are sorted by decreasing T21 vs normal control expression ratio. For simplicity, some segments are not shown because they overlap with those highlighted in one of the listed regions
  2. Chr chromosome, Location segment cytoband derived from that of the first mapped gene within the segment, Segment start/end chromosomal coordinates for each segment