Table 3 Comparison among trisomy 21 (T21) or normal control (n) blood cell transcriptome maps obtained by RNA-Seq (present study) and microarray and RNA-Seq (different studies) experiments and analysed by TRAM. For each comparison, the number of genes in common between the two compared studies, and the number of the unique gene for each study are indicated. For each comparison, Spearman correlation coefficients (r) are calculated on common genes (p<.0001 by the JMP software for all comparisons). WBC white blood cells. Details about the studies used in the following comparisons are listed in Supplementary Table 11

T21 blood cells (RNA-Seq) vs T21 WBC (array) [11]

19,378

24,699

4,336

9,657

15,042

0.7353

n blood cells (RNA-Seq) vs n WBC (array) [11]

19,357

24,699

4,316

9,658

15,041

0.7319

T21/n blood cells (RNA-Seq) vs T21/n WBC (array) [11]

17,867

24,699

3,414

10,246

14,453

0.1193

T21 blood cells (RNA-Seq) vs T21 WBC (RNA-Seq) [32]

19,378

22,614

3,194

6,430

16,184

0.7137

n blood cells (RNA-Seq) vs n WBC (RNA-Seq) [32]

19,357

21,099

3,259

5,001

16,098

0.7097

T21/n blood cells (RNA-Seq) vs T21/n WBC [32]

17,867

20,826

2,517

5,476

15,350

0.1718

T21 WBC (array) [11] vs T21 WBC [32]

24,699

22,614

6,082

3,997

18,617

0.8702

n WBC (array) [11] vs n WBC [32]

24,699

21,099

6,835

3,235

17,864

0.8721

T21/n WBC (array) [11] vs T21/n WBC [32]

24,699

20,826

6,939

3,066

17,760

0.3354