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Table 4 Association between TMPRSS2 polymorphism with mortality/survival in patients with moderate-severe COVID-19

From: Initial study on TMPRSS2 p.Val160Met genetic variant in COVID-19 patients

 

Moderate COVID-19 (N=32)

Severe COVID-19 (N=30)

 

Recovered (N=29, 90.6%)

Died (N=3, 9.4%)

Recovered (N=12, 30%)

Died (N=18, 60%)

Genotype (amino acids)

 CC (Val/Val)

16 (50%)

1 (3.1%)

3 (10 %)

10 (33.3%)

 CT (Val/Met)

10 (31.3%)

1 (3.1%)

4 (13.3%)

6 (20 %)

 TT (Met/Met)

3 (9.4%)

1 (3.1%)

5 (16.7%)

2 (6.7%)

 

Chi-square test P=0.498

Chi-square test P=0.109

 

Linear-by-linear chi-square association test P=0.299

Linear-by-linear chi-square association test P=0.042