Table 6 Association results between blood cell count traits and MT-CN polygenic risk score in 357656 UK Biobank samples. β refers to the regression coefficient of MT-CN in a linear regression of cell type onto MT-CN PRS and other covariates (see Methods). Bolded results are significant below a nominal α = 0.05.
Cell type | All samples | No post hoc high-leverage outliers | ||||
|---|---|---|---|---|---|---|
β | SE | P | β | SE | P | |
Leukocyte | − 0.00856 | 0.00170 | 4.42 × 10-7 | - | - | - |
Monocyte | − 0.00119 | 0.00170 | 0.482 | - | - | - |
Lymphocyte | − 0.00250 | 0.00170 | 0.142 | - | - | - |
Neutrophil | − 0.00954 | 0.00169 | 1.80 × 10-8 | − 0.00948 | 0.00169 | 2.17 × 10-8 |
Platelet | 0.00548 | 0.00170 | 1.24 × 10-3 | 0.00548 | 0.00170 | 1.25 × 10-3 |