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Fig. 2 | Human Genomics

Fig. 2

From: HCP5, as the sponge of miR-1291, facilitates AML cell proliferation and restrains apoptosis via increasing PIK3R5 expression

Fig. 2

HCP5 induced the promotion of cell viability and inhibition of apoptosis in AML cells. (A) The expression of HCP5 in HS-5, K562, and THP-1 cells was detected by qRT-PCR. (B) The transfection of si-HCP5 evidently decreased the expression of HCP5 in THP-1 cells. (C) K562 cells transfected with pcDNA3.1-HCP5 showed an increase HCP5 level. (D) Treated AML cell viability was examined with CCK-8 analysis. (E) The rate of apoptosis in THP-1 and K562 cells was assessed using flow cytometry experiment. **P < 0.01 versus HS-5, si-con, or vector

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