Table 2 The topology properties of 41 hub genes (The genes are ranked by degree)
Genes | Degree | Betweenness centrality | Closeness centrality | Clustering coefficient | Stress | Average shortest path length |
|---|---|---|---|---|---|---|
CDC20 | 41 | 4.09E-02 | 9.36E-01 | 7.48E-01 | 446 | 1.07 |
CDK1 | 40 | 2.89E-02 | 9.17E-01 | 7.79E-01 | 398 | 1.09 |
TOP2A | 40 | 3.73E-02 | 9.17E-01 | 7.67E-01 | 394 | 1.09 |
BUB1B | 39 | 1.65E-02 | 8.98E-01 | 7.99E-01 | 320 | 1.11 |
CCNB2 | 39 | 1.06E-02 | 8.98E-01 | 8.19E-01 | 284 | 1.11 |
NCAPG | 39 | 2.64E-02 | 8.98E-01 | 7.96E-01 | 354 | 1.11 |
ASPM | 39 | 1.50E-02 | 8.98E-01 | 8.08E-01 | 302 | 1.11 |
AURKA | 38 | 8.26E-03 | 8.80E-01 | 8.45E-01 | 232 | 1.14 |
MAD2L1 | 38 | 7.61E-03 | 8.80E-01 | 8.48E-01 | 224 | 1.14 |
CCNB1 | 38 | 7.61E-03 | 8.80E-01 | 8.48E-01 | 224 | 1.14 |
DLGAP5 | 37 | 9.50E-02 | 8.63E-01 | 8.45E-01 | 216 | 1.16 |
KIF20A | 37 | 1.05E-02 | 8.63E-01 | 8.54E-01 | 211 | 1.16 |
PBK | 37 | 5.79E-03 | 8.63E-01 | 8.74E-01 | 180 | 1.16 |
CENPF | 37 | 1.16E-02 | 8.63E-01 | 8.44E-01 | 222 | 1.16 |
RRM2 | 37 | 5.51E-03 | 8.63E-01 | 8.75E-01 | 174 | 1.16 |
MELK | 37 | 6.29E-03 | 8.63E-01 | 8.72E-01 | 178 | 1.16 |
NDC80 | 36 | 4.01E-03 | 8.46E-01 | 8.98E-01 | 134 | 1.18 |
PTTG1 | 35 | 3.72E-03 | 8.30E-01 | 9.08E-01 | 116 | 1.20 |
BIRC5 | 35 | 3.14E-03 | 8.30E-01 | 9.18E-01 | 102 | 1.20 |
TTK | 35 | 2.84E-03 | 8.30E-01 | 9.23E-01 | 96 | 1.20 |
PRC1 | 35 | 2.20E-03 | 8.30E-01 | 9.29E-01 | 88 | 1.20 |
HMMR | 35 | 4.80E-02 | 8.30E-01 | 9.81E-01 | 350 | 1.20 |
KIAA0101 | 35 | 5.88E-03 | 8.30E-01 | 8.81E-01 | 148 | 1.20 |
DTL | 35 | 6.38E-03 | 8.30E-01 | 8.74E-01 | 158 | 1.20 |
NEK2 | 34 | 3.29E-03 | 8.15E-01 | 9.20E-01 | 96 | 1.23 |
NUF2 | 34 | 2.92E-03 | 8.15E-01 | 9.20E-01 | 94 | 1.23 |
CDKN3 | 34 | 3.07E-03 | 8.15E-01 | 9.23E-01 | 90 | 1.23 |
RACGAP1 | 33 | 9.43E-04 | 8.00E-01 | 9.62E-01 | 42 | 1.25 |
KIF4A | 33 | 2.22E-03 | 8.00E-01 | 9.45E-01 | 62 | 1.25 |
RAD51AP1 | 32 | 7.50E-04 | 7.86E-01 | 9.68E-01 | 34 | 1.27 |
ECT2 | 31 | 2.28E-04 | 7.72E-01 | 9.87E-01 | 12 | 1.30 |
ANLN | 31 | 2.20E-04 | 7.72E-01 | 9.87E-01 | 12 | 1.30 |
TYMS | 30 | 1.19E-03 | 7.59E-01 | 9.52E-01 | 46 | 1.32 |
CKAP2 | 27 | 0.00 | 7.21E-01 | 1.00 | 0 | 1.39 |
MCM6 | 25 | 1.14E-02 | 6.88E-01 | 8.30E-01 | 130 | 1.45 |
UHRF1 | 19 | 1.07E-03 | 6.29E-01 | 9.36E-01 | 22 | 1.60 |
UBE2T | 19 | 0.00 | 6.29E-01 | 1.00 | 0 | 1.60 |
CENPK | 14 | 0.00 | 5.87E-01 | 1.00 | 0 | 1.70 |
GMNN | 13 | 9.00E-05 | 5.79E-01 | 9.74E-01 | 4 | 1.73 |
FAM83D | 12 | 0.00 | 5.71E-01 | 1.00 | 0 | 1.75 |
HELLS | 11 | 2.63E-04 | 5.64E-01 | 9.09E-01 | 10 | 1.77 |