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Fig. 7 | Human Genomics

Fig. 7

From: Identification of subgroups along the glycolysis-cholesterol synthesis axis and the development of an associated prognostic risk model

Fig. 7

Build the risk model by LASSO. A Cross validation based on C-index to determine the best choice of genes in the model. B Genes in the different combinations and their corresponding coefficients. C–E Patients of training set were arranged in the same ascending order of the risk score. F–H Patients of internal validation set were arranged in the same ascending order of the risk score. I–K Patients of GSE19234 data set were arranged in the same ascending order of the risk score. C, F, I Patients were divided into different risk levels according to the median of the risk scores in their respective data sets. D, G, J The relationship between the survival outcome and risk levels of patients. Low-risk patients were shown on the left side of the dotted line and high-risk patients were shown on the right side. E, H, K Heat maps for the genes in the signature. LASSO, least absolute shrinkage and selection operator. And P < 0.05 is defined as statistically significant

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Human Genomics

ISSN: 1479-7364