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Table 2 Univariate Cox results and Lasso coefficients for risk score formula of genes

From: Identification of subgroups along the glycolysis-cholesterol synthesis axis and the development of an associated prognostic risk model

 

HR

95% CI

P value

Lasso coefficient

KIFC1

1.7

(1.1–2.6)

0.016

0.345468464

GPR19

1.6

(1.1–2.4)

0.016

0.272311029

SLC45A3

1.6

(1.1–2.2)

0.016

0.645641342

TYMS

1.5

(0.98–2.2)

0.064

0.525818769

PLK1

1.5

(1–2.3)

0.029

0.111452595

IQGAP3

1.5

(1–2.3)

0.027

0.34671539

CDCA8

1.5

(0.98–2.2)

0.06

1.060191747

UHRF1

1.4

(1–2.1)

0.047

0.464561353

RRM2

1.3

(0.91–1.9)

0.15

0.208350724

CCNA2

1.3

(0.87–1.9)

0.21

0.218089206

CEP55

1.3

(0.85–1.8)

0.26

0.276731331

TK1

1.3

(0.89–2)

0.17

−0.870357919

PBK

1.2

(0.82–1.6)

0.39

0.04492278

DIAPH3

1.2

(0.86–1.8)

0.25

0.546604919

SHCBP1

1.2

(0.79–1.8)

0.41

0.462985398

DEPDC1B

1.2

(0.8–1.8)

0.35

0.501249454

MELK

1.2

(0.8–1.7)

0.42

−0.311001546

BZW2

1.2

(0.81–1.9)

0.32

0.068764877

TFRC

1.1

(0.83–1.6)

0.43

0.066927634

PRR11

1.1

(0.76–1.6)

0.59

−0.193881148

CDC6

1.1

(0.76–1.7)

0.51

−0.27245389

NUSAP1

1.1

(0.72–1.6)

0.68

−0.059609277

E2F7

1.1

(0.76–1.6)

0.58

−0.984225964

ESCO2

1.1

(0.68–1.8)

0.71

0.514700781

INCENP

1.1

(0.67–1.7)

0.74

−0.484422932

BRIP1

1.1

(0.7–1.8)

0.61

−0.123046978

CDCA7L

1

(0.84–1.3)

0.71

−0.016050038

RCOR2

1

(0.77–1.3)

0.97

−0.183697727

NCAPG

1

(0.72–1.4)

0.9

−0.041934418

GPC2

1

(0.73–1.5)

0.85

0.279342277

PGM1

1

(0.7–1.4)

0.99

0.048131126

C3orf52

1

(0.68–1.6)

0.88

0.372435672

LMNB1

0.99

(0.67–1.5)

0.94

−0.388549559

BRCA1

0.98

(0.62–1.5)

0.93

−0.041497529

ATAD2

0.95

(0.63–1.4)

0.79

0.323810656

EZH2

0.93

(0.61–1.4)

0.75

−0.289895316

TTK

0.92

(0.63–1.3)

0.66

–0.623252924

SMC2

0.82

(0.57–1.2)

0.29

−0.120862539

LBR

0.8

(0.56–1.1)

0.22

−0.486321723

HMGB2

0.79

(0.54–1.2)

0.23

−0.222782483

ODC1

0.78

(0.58–1.1)

0.12

−0.502894698

SASS6

0.76

(0.48–1.2)

0.22

0.033157158

PSRC1

0.7

(0.47–1)

0.08

−0.63407795

USP1

0.67

(0.47–0.95)

0.024

−0.981142492

  1. Forty-four genes were selected by Lasso, and univariate Cox regression was performed on them. HR, hazard ratio; CI, confidence interval; Lasso, least absolute shrinkage and selection operator