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Table 3 Univariate and multivariate Cox regression for clinical variables and the prognostic risk model in international validation group

From: Identification of subgroups along the glycolysis-cholesterol synthesis axis and the development of an associated prognostic risk model

Prognostic index

Univariate analysis

Multivariate analysis

 

HR (95% CI)

P value

HR (95% CI)

P value

TCGA SKCM set (n = 92)

Age

1.021 (1.003–1.039)

0.022

1.015 (0.995–1.035)

0.148

Gender

0.837 (0.496–1.411)

0.504

  

Race

1.102 (0.15–8.089)

0.924

  

Pathological stage

1.406 (1.023–1.932)

0.035

0.745 (0.43–1.292)

0.295

Pathological M

47.619 (10.351–219.066)

< 0.001

21.963 (4.23–114.032)

< 0.001

Pathological N

1.407 (1.081–1.831)

0.011

1.68 (1.114–2.533)

0.013

Pathological T

1.319 (1.1–1.582)

0.003

1.324 (1.058–1.658)

0.014

Risk score

1.699 (1.118–2.582)

0.013

1.351 (1.112–1.631)

0.027

  1. T, tumor; N, lymph node; HR, hazard ratio; CI, confidence intervals