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Table 2 GO analysis of the candidate miRNAs in TRD

From: Abnormal expression profile of plasma-derived exosomal microRNAs in patients with treatment-resistant depression

Term

Overlap

P-values

Axon part (GO:0033267)

32/415

0.003757

CHD-type complex (GO:0090545)

4/18

0.008459

Cytoplasmic ribonucleoprotein granule (GO:0036464)

23/268

0.003642

Early endosome (GO:0005769)

34/434

0.002231

NuRD complex (GO:0016581)

4/18

0.008459

PML body (GO:0016605)

13/113

0.002301

Postsynaptic density (GO:0014069)

25/35

0.006811

Ribonucleoprotein granule (GO:0035770)

23/281

0.006435

Transcription factor complex (GO:0005667)

33/403

0.001257

Transcriptional repressor complex (GO:0017053)

11/90

0.003031

Appendage development (GO:0048736)

23/188

0.000026

Axonogenesis (GO:0007409)

46/498

0.000010

Cell fate commitment (GO:0045165)

34/304

0.000003

Embryonic organ development (GO:0048568)

43/480

0.000041

Limb development (GO:0060173)

23/188

0.000026

Lung development (GO:0030324)

23/193

0.000040

Positive regulation of neuron differentiation (GO:0045666)

41/402

0.000003

Positive regulation of neuron projection development (GO:0010976)

32/304

0.000018

Regulation of cellular component size (GO:0032535)

39/407

0.000021

Regulation of transcription involved in cell fate commitment (GO:0060850)

7/18

0.000010

DNA-binding transcription activator activity, RNA polymerase II-specific (GO:0001228)

46/479

0.000009

GTP binding (GO:0005525)

33/406

0.002841

Guanyl nucleotide binding (GO:0019001)

35/429

0.002028

Guanyl ribonucleotide binding (GO:0032561)

35/429

0.002028

Nucleoside binding (GO:0001882)

33/422

0.005119

Purine nucleoside binding (GO:0001883)

33/414

0.003839

Purine ribonucleoside binding (GO:0032550)

33/411

0.003434

Ribonucleoside binding (GO:0032549)

33/415

0.003982

SUMO transferase activity (GO:0019789)

5/20

0.002265

Transcription corepressor activity (GO:0003714)

22/195

0.000214