Table 4 Putative target genes of the differentially expressed miRNAs in plasma-derived exosomes in four patients with TRD compared to four healthy control subjects

ADRA1B

1 (has-miR-1292-3p)

Down

[33]

GABA, serotonin

ADRB1

1 (has-miR-1292-3p)

Down

[34]

Synapsin

CACNA1C

1 (has-miR-1292-3p)

Down

[35]

Synapsin Dopamine Glutamate Adrenergic

CREB1

1 (has-miR-1292-3p)

Down

[36]

Synapsin Dopamine NMDA Glutamate serotonin

FGFR1

1 (has-miR-1292-3p)

Down

[37]

Dopamine

GNAS

1 (has-miR-1292-3p)

Down

[38]

Synapsin Glutamate serotonin

GRIK5

1 (has-miR-1292-3p)

Down

[33]

Synapsin Dopamine NMDA Glutamate GABA

HTR1A

1 (has-miR-1292-3p)

Down

[39]

Synapsin Glutamate

NOS1

1 (has-miR-1292-3p)

Down

[40]

Serotonin Dopamine NMDA Glutamate GABA Adrenergic

OPRM1

1 (has-miR-1292-3p)

Down

[41]

Synapsin Dopamine Glutamate GABA Adrenergic

P2RX7

1 (has-miR-1292-3p)

Down

[42]

Glutamate GABA

PDE10A

1 (has-miR-1292-3p)

Down

[43]

Synapsin

NUFIP2

1 (has-miR-335-5p)

Up

[44]

MDD

TCF4

1 (has-miR-335-5p)

Up

[44]

MDD